High Prevalence of Foot Insufficiency Fractures in Patients With Inflammatory Rheumatic Musculoskeletal Diseases
Authors' conclusion
A high prevalence of foot fractures was found in MRI scans of patients with RMD, many without osteoporosis. MRI was more sensitive than radiographs to detect IF.
Study context
- Population
- Consecutive patients with rheumatic musculoskeletal disease (RMD) presenting with foot pain undergoing magnetic resonance imaging (MRI), 2 time periods between 2016 and 2018
- Participants
- 1,752 MRI scans
- Exposure
- Inflammatory vs noninflammatory RMD
- Inflammatory RMDn = 1,145
- Noninflammatory RMDn = 607reference
- Outcome
- Prevalence of foot insufficiency fractures (IF) on MRI
Methodological detailsconsecutive patients, matched controls, multivariate analyses
- Consecutive patients
- Matched controls
- Multivariate analyses
Main finding
As reported in the abstract
Foot IF prevalence
P < 0.001
- Foot insufficiency fractures (IF), all MRI scans
- 129 (7.5%)
Observational data: associations, not effects.
Further findings
IF prevalence by diagnosis (subgroup)
- Connective tissue disease (CTD)
- 23%
- Rheumatoid arthritis (RA)
- 11.4%
- Highest in CTD and RA
IF detected by conventional radiography
- IF detected on radiography
- 25%
Low bone mineral density (BMD) and history of fractures, IF vs no IF
- Low BMD, IF vs no IF
- 42.6% vs 16.2%
- History of fractures, IF vs no IF
- 34.9% vs 8.6%
- P < 0.001
Original publication
High Prevalence of Foot Insufficiency Fractures in Patients With Inflammatory Rheumatic Musculoskeletal Diseases. J Rheumatol. Published 15 December 2022. doi:10.
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