Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study
Authors' conclusion
We identified gait alterations associated with worsening knee pain and those associated with worsening physical function.
Study context
- Population
- Participants in the Multicenter Osteoarthritis Study (MOST) who completed a 20-m walk test wearing inertial sensors on the lower back and ankles
- Participants
- 2,324 participants
- Outcome
- Worsening knee pain and worsening physical function
- Follow-up
- Two years
Methodological detailsmulticentre, machine learning (super learning), log-binomial regression, mediation analysis
- Multicentre
- Machine learning (super learning)
- Log-binomial regression
- Mediation analysis
Main finding
As reported in the abstract
Worsening knee pain
29%
Worsening function
24%
Observational data: associations, not effects.
Further findings
Mediation by pain
- Worsening pain partially mediated the association of cadence with function
Original publication
Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). Published 17 April 2024. doi:10.
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