Systemic sclerosis & Raynaud's
Frequency-specific microcurrent improves hand function and Raynaud’s symptoms in scleroderma: results of two pilot studies
Authors' conclusion
The degree of improvement in hand function obtained over a very short treatment period of 45 min to 1 h was significant.
Study context
- Population
- Patients with SSc
- Participants
- 17 patients2 pilot studies
- Comparison
- Frequency-specific microcurrent, before vs after treatment
- Frequency-specific microcurrentn = 17
- Outcome
- Hand function (Cochin hand function score) before and after treatment
Methodological detailstwo uncontrolled before–after studies, two separate pilot studies, pre–post treatment comparison
- Two uncontrolled before–after studies
- Two separate pilot studies
- Pre–post treatment comparison
Main finding
As reported in the abstract
Hand function (Cochin hand function score), average improvement · post-treatment
Average improvement, second pilot study
38%
95% CI 22%–55%P = 0.002
Average improvement, both studies combined
40%
95% CI 26%–55%P = 0.0001
Further findings
Raynaud's symptom severity (VAS, out of 100), mean improvement pre- vs post-treatment
- Mean improvement in Raynaud's VAS
- 18 points (95% CI 3.3-33 points, P = 0.016)
Original publication
Frequency-specific microcurrent improves hand function and Raynaud’s symptoms in scleroderma: results of two pilot studies. Rheumatology (Oxford). Published 4 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →