Frailty and risk of subsequent fracture among older adults presenting to hospital with a minimal trauma fracture
Authors' conclusion
Our results indicate that following an initial minimal trauma fracture, frailty independently increases the risk of a subsequent fracture.
Study context
- Population
- Older adults (aged 60 years or more) presenting to hospital with a minimal trauma fracture, January 2014–December 20208,371 women [69%]
- Participants
- 12,115 adults
- Exposure
- Increasing cumulative frailty deficit item groups
- Outcome
- Subsequent fracture by frailty status (cumulative deficit approach) at the time of initial fracture
Methodological detailsCox's proportional hazard model, adjusted for sex, age, and site of initial fracture
- Cox's proportional hazard model
- Adjusted for sex, age, and site of initial fracture
Main finding
As reported in the abstract
Incidence of subsequent fracture by frailty deficit group
1 deficit item
25.0
95% CI 22.4–27.8 · per 1000 older adults
4 to 12 deficit items
31.8
95% CI 28.0–35.8 · per 1000
- Increasing number of frailty deficit items associated with increased risk of subsequent fracture, adjusted for age, sex and site of initial fracture
- P for trend = 0.008
Observational data: associations, not effects.
Further findings
Subsequent fractures during follow-up (all participants)
- Subsequent fractures
- 1137 (9.4%)
Original publication
Frailty and risk of subsequent fracture among older adults presenting to hospital with a minimal trauma fracture. Osteoporos Int. Published 6 December 2022. doi:10.
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