Osteoporosis & bone health

Estimating the economic burden of osteoporotic fractures in a multinational study: a real-world data perspective

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

The current study demonstrates the substantial economic burden of OF across different countries when compared with matched non-OF patients.

Study context

Population
Women aged ≥ 50 years in Australia, Germany, South Korea, Spain, and the USAmatched cohort
Exposure
Newly identified osteoporotic fracture vs propensity score-matched cohort without osteoporotic fracture
Outcome
Healthcare resource utilization and direct costs of care
Follow-up
S of up to 5 years
Methodological detailsmultinational, matched cohort, propensity score-matched, standardized methodology across healthcare systems
  • Multinational
  • Matched cohort
  • Propensity score-matched
  • Standardized methodology across healthcare systems

Main finding

As reported in the abstract

up to 5 years
  • Significantly higher rates and length of inpatient admissions in the osteoporotic fracture (OF) cohort across all five countries
  • Adjusted total costs of care ratio between OF and non-OF cohorts significant in each country
  • Adjusted cost ratios for pharmacy, inpatient care, emergency care, and outpatient visits similarly higher in the OF cohort across countries
  • Matched cohort
  • Propensity score-matched

Observational data: associations, not effects.

Original publication

Estimating the economic burden of osteoporotic fractures in a multinational study: a real-world data perspective. Osteoporos Int. Published 31 August 2023. doi:10.1007/s00198-023-06895-4

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