Across rheumatic diseases

Effect of high-intensity interval training in physiotherapy primary care for patients with inflammatory arthritis: the ExeHeart randomised controlled trial

RMD OpenPublished Randomised controlled trial

Primary result · VO2peakResult — go to the resultBetween-group difference 2.5 mL/kg/min 95% CI 0.9–4.0

Authors' conclusion

After 12 weeks of supervised HIIT delivered in physiotherapy primary care, patients with IA demonstrated a favourable improvement in CRF, with sustained effects at 6-month follow-up.

Study context

Population
Patients with inflammatory arthritis in physiotherapy primary care
Participants
60 patients
Comparison
Usual care plus 12 weeks of individualised high-intensity interval training (HIIT) vs usual care
Primary endpoint
Cardiorespiratory fitness (CRF) (VO2peak)
Follow-up
3 months
Methodological detailssingle-blinded
  • Single-blinded

Primary result

VO2peak

Between-group difference

2.5 mL/kg/min

95% CI 0.9–4.0

Exercisevs Control
between-group difference 2.5 mL/kg/min (95% CI 0.9–4.0)

As reported in the abstract

Secondary outcomes

OutcomeBetween-group difference (mL/kg/min) (95% CI)
VO2peak · 6 monthsIntention-to-treat2.6 (0.8–4.3)

Self-reported physical activity · 3 and 6 months

Beneficial change in favour of the exercise group

Cardiovascular disease (CVD) risk factors, disease impact, pain, fatigue, exercise beliefs and self-efficacy

Differences generally small and non-significant

Safety

Tolerability, adverse events and disease activity

HIIT well-tolerated with minimal adverse events and no apparent impact on disease activity

Original publication

Effect of high-intensity interval training in physiotherapy primary care for patients with inflammatory arthritis: the ExeHeart randomised controlled trial. RMD Open. Published 18 January 2024. doi:10.1136/rmdopen-2023-003440

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