Fibromyalgia & musculoskeletal pain
Determining the Patient Acceptable Symptom State (PASS) cut-off points for the Fibromyalgia Impact Questionnaire (FIQR), FASmod and PSD in patients with fibromyalgia: a registry-based study
Authors' conclusion
The FIQR, FASmod, and PSD PASS cut-off points for FM patients have never been determined before.
Study context
- Population
- Fibromyalgia (FM) patients in the Italian Fibromyalgia Registry (IFR)5,545 women · 369 males
- Exposure
- FIQR vs FASmod vs PSD PASS cut-offs
- Outcome
- PASS cut-off values for FIQR, FASmod and PSD (dichotomous PASS answer; ROC analyses)
Methodological detailsregistry-based, ROC analyses, multivariate logistic regression
- Registry-based
- ROC analyses
- Multivariate logistic regression
Main finding
As reported in the abstract
PASS threshold
| Group | Value | AUC |
|---|---|---|
| FIQR | ≤58 | 0.819 |
| FASmod | ≤23 | 0.805 |
| PSD | ≤16 | 0.773 |
Value
FIQR≤58
FASmod≤23
PSD≤16
AUC
FIQR0.819
FASmod0.805
PSD0.773
- FIQR vs FASmod: P = 0.0124 — FIQR PASS outperforms
- FIQR vs PSD: P < 0.0001 — FIQR PASS outperforms
Observational data: associations, not effects.
Further findings
Patients reporting acceptable symptom state
- Patients in PASS
- 27.8%
- Patients in PASS differed in all patient-reported outcome measures
- P < 0.001
Predictors of PASS (multivariate logistic analysis)
- FIQR items related to memory and pain were the only predictors of PASS
Original publication
Determining the PASS cut-off points for the FIQR, FASmod and PSD in patients with fibromyalgia: a registry-based study. Clin Exp Rheumatol. Published 22 December 2022. doi:10.
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