Across rheumatic diseases

COVID‐19 Vaccine Uptake, Hesitancy, and Flare in a Large Rheumatology Practice Network

Arthritis Care Res (Hoboken)Published Cross-sectional study

Main finding · COVID-19 vaccine uptakeResult — go to the resultAdjusted odds ratio 0.68 95% CI 0.65–0.72

Authors' conclusion

Some patients who are vaccine and booster hesitant eventually receive a vaccine dose

Study context

Population
Patients of 108 rheumatology practices in a practice-based network surveyed December 2021 to December 2022
Participants
61,158 patients
Exposure
Patients with vs without autoimmune and inflammatory rheumatic diseases (AIIRDs)
Outcome
COVID-19 vaccine uptake, reasons for hesitancy, and self-reported flare
Methodological detailstablet-based survey, 108 rheumatology practices, multivariable logistic regression
  • Tablet-based survey
  • 108 rheumatology practices
  • Multivariable logistic regression

Main finding

COVID-19 vaccine uptake

Adjusted odds ratio

0.68

95% CI 0.65–0.72

AIIRDvs Without AIIRD
aOR 0.68 (95% CI 0.65–0.72)

As reported in the abstract

At least one vaccine dose (all patients)
89%
At least one booster (of the vaccinated)
68%
Vaccinated patients with AIIRDs vs unvaccinated
44% vs 56%

Observational data: associations, not effects.

Further findings

Vaccine hesitancy

Booster hesitancy

Reasons for hesitancy

Safety concerns (vaccine hesitancy)
28%
Side effects (vaccine hesitancy)
23%
Lack of physician recommendation (booster hesitancy)
23%

Hesitant patients later reporting receiving a dose

Vaccine hesitant
12%
Booster hesitant
39%

Safety

OutcomeaOR (95% CI)
Self-reported flare or worsening disease0.99 (0.94–1.05)

Original publication

COVID‐19 Vaccine Uptake, Hesitancy, and Flare in a Large Rheumatology Practice Network. Arthritis Care Res (Hoboken). Published 12 December 2023. doi:10.1002/acr.25241

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