Clinical features, treatment, and outcomes of celiac-associated arthritis: a retrospective cohort study
Authors' conclusion
Rheumatologists play an important role in the identification of celiac disease, as arthritis was the presenting symptom in most cases and was not always associated with GI symptoms or poor growth.
Study context
- Population
- Children with celiac disease seen in pediatric rheumatology clinic for joint complaints, 2004–202113 diagnosed with arthritis
- Participants
- 29 children
- Outcome
- Clinical features of celiac-associated arthritis (n=13)
Main finding
As reported in the abstract
- Mean age, years (SD 5.9)
- 8.9
- Female
- 61.5%
- Celiac disease diagnosed before arthritis
- 2 (15.4%)
- Celiac testing initiated by rheumatologist
- 6 (46.2%)
- Concomitant GI symptoms
- 8 (61.5%)
- Oligoarticular presentation
- 76.9%
- Asymmetric presentation
- 84.6%
- Required systemic therapy (DMARDs, biologics, or both)
- 11 (84.6%)
Observational data: associations, not effects.
Further findings
Stopped systemic medications among 10 on systemic therapy compliant with gluten-free diet
- Stopped systemic medications
- 3 (30%)
- Patients who cleared celiac serologies and came off systemic medications
- 2 of 3
Change between index and final visit
- Significant improvement in number of joints involved
- P = 0.02
- Significant improvement in PGA of disease activity
- P = 0.03
- Wilcoxon signed-rank tests
Original publication
Clinical features, treatment, and outcomes of celiac-associated arthritis: a retrospective cohort study. Pediatr Rheumatol Online J. Published 2 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →