Pediatric rheumatology

Clinical course, complications and treatment outcomes in Still’s disease: a 10-year single-centre cohort study

RMD OpenPublished Retrospective cohort study

Authors' conclusion

This 10-year cohort demonstrates marked heterogeneity in Still's disease/sJIA. MAS and ILD frequently co-occur and indicate a more aggressive course.

Study context

Population
Patients with Still's disease/sJIA followed 2015–2025 at a tertiary paediatric rheumatology centre
Participants
110 patients
Outcome
Complications and disease course
Methodological detailssingle-centre, observational, logistic regression
  • Single-centre
  • Observational
  • Logistic regression

Main finding

As reported in the abstract

Macrophage activation syndrome (MAS) occurrence

36.7%

Interstitial lung disease (ILD) occurrence

8.2%

Observational data: associations, not effects.

Original publication

Clinical course, complications and treatment outcomes in Still’s disease: a 10-year single-centre cohort study. RMD Open. Published 12 May 2026. doi:10.1136/rmdopen-2025-006637

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