Across rheumatic diseases

Association of vocational interventions and work-related factors with disease and work outcomes in people with rheumatic and musculoskeletal diseases (RMDs): A systematic review

Semin Arthritis RheumPublished Systematic review

Authors' conclusion

Many studies indicated that work participation is not likely to be detrimental and, in some cases, may be beneficial for RMD-specific outcomes

Study context

Population
People with OA, rheumatoid arthritis (RA), SLE, axial spondyloarthritis (axSpA), PsA, systemic sclerosis (SSc) and gout2 systematic literature reviews (SLRs) and 23 original manuscripts
Methodological detailstwo separate systematic literature reviews, EULAR taskforce, SLRs published 01/2013–09/2018; original studies published before 05/2019, Medline, Embase, Cochrane Library of systematic reviews and CENTRAL searched, Most manuscripts (43.5%) included people with RA; none on gout
  • Two separate systematic literature reviews
  • EULAR taskforce
  • SLRs published 01/2013–09/2018; original studies published before 05/2019
  • Medline, Embase, Cochrane Library of systematic reviews and CENTRAL searched
  • Most manuscripts (43.5%) included people with RA; none on gout

Pooled result

As reported in the abstract

  • Most observational studies evaluated association of work-related factors with work outcomes; limited information on impact of work on clinical outcomes
  • Physically demanding jobs: small detrimental effect on radiographic progression in axSpA and PsA (a few studies)
  • Vocational interventions: beneficial effects on disease-specific outcomes, small effect sizes

Original publication

Association of vocational interventions and work-related factors with disease and work outcomes in people with RMDs: A systematic review. Semin Arthritis Rheum. Published 13 November 2022. doi:10.1016/j.semarthrit.2022.152135

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