Association between rheumatoid arthritis flares and joint structural changes at 24 months: using FLARE-RA questionnaire
Authors' conclusion
The FLARE-RA score was associated with physician-based disease activity measures, suggesting its value as a patient-reported disease-activity measure in routine care, including remote consultation.
Study context
- Population
- Adults with rheumatoid arthritis (RA) for less than 10 years and Health Assessment Questionnaire-Disability Index (HAQ-DI) score<1; FLARE-RA questionnaire every 3 months at home, for 24 monthsanalysed
- Participants
- 221 adults
- Outcome
- Joint structural damage progression (wrist and foot X-rays) predicted by FLARE-RA flares
- Follow-up
- 24 months
Methodological detailslogistic regression, generalized linear mixed-effects models
- Logistic regression
- Generalized linear mixed-effects models
Main finding
As reported in the abstract
month 24
Structural changes, OR (95% CI 0.99-1.01); not associated
1.00
Progression of erosions, OR (95% CI 0.99-1.01); not associated
1.00
Observational data: associations, not effects.
Further findings
Association of FLARE-RA global score with DAS28, PGA, HAQ-DI, Patient Acceptable Symptom State, MCID and treatment intensification during follow-up
- Significantly associated (all P<0.0001)
Original publication
Association between rheumatoid arthritis flares and joint structural changes at 24 months: using FLARE-RA questionnaire. Joint Bone Spine. Published 2 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →