Association between dental diseases and oral hygiene care and the risk of vertebral fracture: a nationwide cohort study
Authors' conclusion
Periodontal disease, dental caries, and an increased number of missing teeth were independently associated with higher risks for vertebral fractures.
Study context
- Population
- Individuals aged ≥40 years who underwent Korean National Health Insurance Service health examinations in 2008, followed up until December 31, 20179.3-year median follow-up
- Participants
- 2,532,253 individuals
- Exposure
- Dental diseases and oral hygiene care vs their absence
- Outcome
- Vertebral fractures
Methodological detailsmultivariable Cox proportional hazard regression
- Multivariable Cox proportional hazard regression
Main finding
As reported in the abstract
Vertebral fracture
Hazard ratio (95% CI)
Periodontal diseasesvs Without dental diseases
1.04(1.02–1.07)
Dental cariesvs Without dental diseases
1.02(1.00–1.05)
≥15 missing teethvs Without dental diseases
1.12(1.05–1.20)
Professional dental cleaning ≥1 time/yearvs Professional dental cleaning <1 time/year
0.89(0.86–0.91)
Toothbrushing ≥2 times/dayvs Toothbrushing 0-1 time/day
0.90(0.87–0.93)
- Vertebral fractures overall
- 1.46% (n = 36,857)
Observational data: associations, not effects.
Further findings
- Better oral hygiene care reduced vertebral fracture risk associated with dental diseases
- all P <0.001
- Combined dental diseases significantly associated with increased vertebral fracture risk; combined oral hygiene care associated with further risk reduction
Original publication
Association between dental diseases and oral hygiene care and the risk of vertebral fracture: a nationwide cohort study. Osteoporos Int. Published 14 December 2023. doi:10.
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