Pediatric rheumatology

Association between asthma and juvenile idiopathic arthritis in children in the United States: a propensity score weighted cross-sectional study

Pediatr Rheumatol Online JPublished Cross-sectional study

Authors' conclusion

After adjusting for sociodemographic and environmental confounders, asthma was independently associated with approximately twice the odds of JIA.

Study context

Population
Children aged 0–17 years, National Survey of Children’s Health (2016–2021), six cycles, US
Participants
169,786 children
Exposure
Asthma vs no asthma
  • Asthman = 14,236
  • Without asthman = 155,550reference
Outcome
Juvenile idiopathic arthritis (JIA) (parent-reported, provider-diagnosed)
Methodological detailspropensity score weighted, generalized boosted modeling, population-based
  • Propensity score weighted
  • Generalized boosted modeling
  • Population-based

Main finding

As reported in the abstract

JIA prevalence and odds
Asthma vs Without asthmaOdds ratio (95% CI)P value
After PSW adjustment
2.10(1.56–2.81)
P < 0.0001
Unweighted
3.56(2.87–4.38)
P < 0.0001

Observational data: associations, not effects.

Original publication

Association between asthma and juvenile idiopathic arthritis in children in the United States: a propensity score weighted cross-sectional study. Pediatr Rheumatol Online J. Published 12 March 2026. doi:10.1186/s12969-026-01202-x

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