Ambulatory Blood Pressure in Patients With Rheumatoid Arthritis: Association With Immune Activation
Authors' conclusion
Despite similar office measurements, 24-hour and nocturnal SBP measurements were higher in patients with RA than in control participants and were strongly associated with inflammation.
Study context
- Population
- Patients with rheumatoid arthritis (RA) and control participants wearing an ambulatory blood pressure (BP) monitor
- Participants
- 46 vs 23
- Exposure
- RA vs control participants
- RAn = 46
- Controln = 23reference
- Outcome
- Ambulatory 24-hour BP and its association with immune activation
Main finding
As reported in the abstract
Median 24-hour ambulatory SBP
P = 0.01
Observational data: associations, not effects.
Further findings
Median diurnal ambulatory SBP
P = 0.003
Median nocturnal ambulatory SBP
P = 0.002
Nocturnal DBP
P = 0.02
Nocturnal BP dipping
P = 0.02
Nocturnal diastolic BP (DBP)
- Other DBP measurements were similar
Association with inflammatory mediators (RA)
- In RA, higher 24-hour and nocturnal systolic BP (SBPs) and less nocturnal dipping strongly correlated with a wide range of inflammatory mediators
- Spearman correlation
Original publication
Ambulatory Blood Pressure in Patients With Rheumatoid Arthritis: Association With Immune Activation. J Rheumatol. Published 15 May 2024. doi:10.
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